The BMI1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to BMI1, and COMMD3-BMI1. This antibody recognizes Human, and Mouse antigen. The BMI1 Rabbit mAb Antibody has been validated for the following applications: Western Blot.
Description
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373)